货号 | 18866-250mg |
描述 | Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.1,2,3 It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitroandin vivomodels.4 |
别名 | Ceftriaxone disodium hemiheptahydrate;Ro 13-9904;Rosihlitazone; |
供应商 | Cayman |
应用文献 | |
1.Bush, K. β-Lactamase inhibitors from laboratory to clinic. Clin.Microbiol.Rev. 1(1), 109-123 (1988). 2.Kalman, D., and Barriere, S.L. Review of the pharmacology, pharmacokinetics, and clinical use of cephalosporins. Texas Heart Institute Journal 17(3), 203-215 (1990). 3.Neu, H.C. The in vitro activity, human pharmacology, and clinical effectiveness of new β-lactam antibiotics. Annual Reviews of Pharmacology and Toxicology 22, 599-642 (1982). 4.Lee, S.G.,Su, Z.Z.,Emdad, L., et al. Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes. The Journal of Biological Chemisty 283(19), 13116-13123 (2008). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 661.6 |
分子式 | C18H16N8O7S3 • 2Na [3.5H2O] |
CAS号 | 104376-79-6 |
稳定性 | ≥ 2 years |
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