Gomisin C
货号：
18643-5mg 基本售价：
350.0 元 规格：
5 mg
产品信息
概述| 货号 | 18643-5mg |
| 描述 | Gomisin C, a lignan first isolated from the fruits of S. chinensis, scavenges oxygen radicals and reduces the production of reactive oxygen species by inhibiting neutrophil activity.1 It has been shown to attenuate respiratory burst in rat peripheral neutrophils via suppression of NADPH oxidase (39% inhibition at 30 µg/ml) and inhibition of cytosolic calcium release from intracellular stores (36% inhibition at 50 µg/ml).2 Gomisin C can induce liver microsomal cytochrome P450, thus facilitating the clearance of xenobiotics and protecting against hepatotoxicity in rodent models of liver injury.3 |
| 别名 | Schisantherin A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Lin, T.J.,Liu, G.T.,Li, X.J., et al. Detection of free radical scavenging activity of schisanhenol by electron spin resonance. Acta.Pharmacol.Sin. 11(6), 534-539 (1990).
2.Wang, J.P.,Raung, S.L.,Hsu, M.f., et al. Inhibition by gomisin C (a lignan from Schizandra chinensis) of the respiratory burst of rat neutrophils. British Journal of Pharmacology 113(3), 945-953 (1994).
3.Li, X.Y. Bioactivity of neolignans from fructus Schizandrae. Mem.Inst.Oswaldo Cruz 86 Suppl 2, 31-37 (1991).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 536.6 |
| 分子式 | C30H32O9 |
| CAS号 | 58546-56-8 |
| 稳定性 | ≥ 2 years |
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