15-deoxy-Δ12,14-Prostaglandin J2
货号:
18570-100ug 基本售价:
350.0 元 规格:
100 ug
产品信息
概述货号 | 18570-100ug |
描述 | 15-deoxy-Δ12,14-Prostaglandin J2(15-deoxy-Δ12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARγ with an EC50 value of 2 µM in a murine chimera system.1,215-deoxy-Δ12,14-PGJ2 is more potent than PGD2, Δ12-PGJ2, and PGJ2 in stimulating lipogenesis in C3H10T1/2 cells. The EC50 for induction of adipocyte differentiation in cultured fibroblasts is 7 µM.1 |
别名 | 15-deoxy-Δ12,14-PGJ2; |
性能供应商 | Cayman |
应用文献 |
1.Kliewer, S.A.,Lenhard, J.M.,Willson, T.M., et al. A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation. Cell 83, 813-819 (1995). 2.Forman, B.M.,Tontonoz, P.,Chen, J., et al. 15-Deoxy-Δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ. Cell 83, 803-812 (1995).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 316.4 |
分子式 | C20H28O3 |
CAS号 | 87893-55-8 |
稳定性 | ≥ 1 year |
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