GSK591
货号:
18354-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 18354-1mg |
描述 | GSK591 is a chemical probe for protein arginine methyltransferase 5 (PRMT5) that potently inhibits the PRMT5/MEP50 complex from methylating histone H4 (IC50 = 11 nM) in vitro. GSK591 is selective for PRMT5 (up to 50 µM) relative to a panel of other methyltransferases. In Z-138 cells, GSK591 inhibits the symmetric arginine methylation of SmD3 with an EC50 value of 56 nM. See the Structural Genomics Consortium (SGC) website for more information. |
别名 | EPZ015866;GSK3203591; |
性能供应商 | Cayman |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 380.5 |
分子式 | C22H28N4O2 |
CAS号 | 1616391-87-7 |
稳定性 | ≥ 2 years |
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