BAY 598
货号：
18238-500ug 基本售价：
350.0 元 规格：
500 ug
产品信息
概述| 货号 | 18238-500ug |
| 描述 | BAY 598 is a selective inhibitor of SMYD2. It inhibits the methylation of p53 at lysine 370 in vitro and in whole cells with IC50 values of 27 nM and <1 µM, respectively.1 BAY 598 exhibits 100-fold selectivity for SMYD2 over other histone methyltransferases and non-epigenetic enzymes. See the Structural Genomics Consortium (SGC) website for more information. |
性能| 供应商 | Cayman |
| 应用文献 |
1.Eggert, E.,Hillig, R.C.,Koehr, S., et al. Discovery and characterization of a highly potent and selective aminopyrazoline-based in vivo probe (BAY-598) for the protein lysine methyltransferase SMYD2. J. Med. Chem. 59(10), 4578-4600 (2016).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 2-8 |
| 纯度 | ≥98% |
| 计算分子量 | 525.3 |
| 分子式 | C22H20Cl2F2N6O3 |
| CAS号 | 1906919-67-2 |
| 稳定性 | ≥ 2 years |
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