(R)-Lansoprazole
货号：
18235-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 18235-10mg |
| 描述 | Lansoprazole (Item No. 13627) is a proton pump inhibitor that irreversibly inactivates the H+/K+-stimulated ATPase pumps in parietal cells, inhibiting gastric acid secretion and increasing intragastric pH.1 It is a 1:1 racemic mixture of (R)-lansoprazole and (S)-lansoprazole, both of which are pharmacologically active.2 (R)-Lansoprazole is an enantiomerically pure form of lansoprazole. It can inhibit acid formation in isolated canine parietal cells with an IC50 value of 59 nM and inhibit the H+/K+-ATPase with an IC50 value of 4.2 µM.2 |
| 别名 | (+)-Lansoprazole;T-168390;TAK-390; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Schubert, M.L. Pharmacotherapy for acid/peptic disorders. Yale Journal of Biology and Medicine 69, 197-201 (1996).
2.Nagaya, H.,Inatomi, N.,Nohara, A., et al. Effects of the enantiomers of lansoprazole (AG-1749) on (H+ + K+)-ATPase activity in canine gastric microsomes and acid formation in isolated canine parietal cells. Biochemical Pharmacology 42(10), 1875-1878 (1991).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 369.4 |
| 分子式 | C16H14F3N3O2S |
| CAS号 | 138530-94-6 |
| 稳定性 | ≥ 2 years |
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