Hydrocortisone 21-hemisuccinate (sodium salt)
货号：
18226-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 18226-100mg |
| 描述 | Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 µM for IL-6).1 It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.2 |
| 别名 | Cortisol 21-hemisuccinate;Hydrocortisone sodium succinate;ST51037292;U-4905; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kang, B.S.,Chung, E.Y.,Yun, Y.P., et al. Inhibitory effects of anti-inflammatory drugs on interleukin-6 bioactivity. Biological and Pharmaceutical Bullentin 24(6), 701-703 (2001).
2.Whitehead, R.H., and Robinson, P.S. Establishment of conditionally immortalized epithelial cell lines from the intestinal tissue of adult normal and transgenic mice. American Journal of Physiology and Gastrointestinal Liver Physiology 296(3), G455-G460 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 484.5 |
| 分子式 | C25H33O8 • Na |
| CAS号 | 125-04-2 |
| 稳定性 | ≥ 2 years |
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