5-deoxy Thymidine
货号：
18154-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 18154-1mg |
| 描述 | The pyrimidine thymidine consists of thymine combined with deoxyribose. Prior to polymerization into DNA, thymidine must be phosphorylated at the hydroxyl group on carbon 5 of the ribose moiety. 5-deoxy Thymidine is a form of thymidine in which the hydroxyl group on carbon 5 of ribose has been replaced with hydrogen. As a result, this compound cannot be phosphorylated and used by DNA polymerase in the synthesis of DNA. 5-deoxy Thymidine is readily imported by cellular nucleoside importers and competitively inhibits the influx of thymidine.1 It demonstrates antibacterial activity against B. subtilisandS. aureus.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Domin, B.A.,Mahony, W.B.,Koszalka, G.W., et al. Membrane permeation characteristics of 5-modified thymidine analogs. Molecular Pharmacology 41(5), 950-956 (1992).
2.Hatano, A.,Nishimura, M., and Souta, I. Impact of unnatural nucleosides on the control of microbial growth. Biocontrol Science 14(2), 55-60 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 226.2 |
| 分子式 | C10H14N2O4 |
| CAS号 | 3458-14-8 |
| 稳定性 | ≥ 2 years |
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