8-Bromoguanosine
货号：
18152-1g 基本售价：
350.0 元 规格：
1 g
产品信息
概述| 货号 | 18152-1g |
| 描述 | 8-Bromoguanosine is a brominated derivative of guanosine. Purine nucleobases with bromine at position eight are known to preferentially adopt the syn conformation as nucleosides and, thus, can be used to reduce the conformational heterogeneity of RNA to potentially enhance its function.1 It is reported to activate lymphocytes through an intracellular mechanism to exert immunostimulatory effects.2,3 |
| 别名 | 2-Amino-8-bromo-6-hydroxypurine riboside;NSC 79211;NSC 174257; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yajima, R.,Proctor, D.J.,Kierzek, R., et al. A conformationally restricted guanosine analog reveals the catalytic relevance of three structures of an RNA enzyme. Chemistry & Biology 14, 23-30 (2007).
2.Goodman, M.G., and Weigle, W.O. Intracellular lymphocyte activation and carrier-mediated transport of C8-substituted guanine ribonucleosides. Proceedings of the National Academy of Sciences of the United States of America 81, 862-866 (1984).
3.Giorgio, S., and Barao, S.C. Intracellular Leishmania amazonensis killing induced by the guanine nucleoside 8-bromoguanosine. Rev.Inst.Med.Trop.S.Paulo. 40(4), 1-9 (1998).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 362.1 |
| 分子式 | C10H12BrN5O5 |
| CAS号 | 4016-63-1 |
| 稳定性 | ≥ 2 years |
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