Xanthosine 5-monophosphate (sodium salt)
货号：
18134-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 18134-10mg |
| 描述 | Xanthosine 5-monophosphate (XMP) is an intermediate in purine metabolism, the product of the rate limiting step in the generation of guanosine monophosphate, which is important for DNA, RNA, and glycoprotein synthesis. XMP is generated from inosine-5’-monophosphate (IMP; Item No. 18135) by IMP dehydrogenase (IMPDH). Inhibitors of IMPDH, including ribavirin (Item No. 16757) and mycophenolate mofetil (Item No. 13988), have potential applications as antiviral and anti-cancer drugs.1,2,3 |
| 别名 | XMP; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Watkins, W.J.,Chen, J.M.,Cho, A., et al. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH. Bioorganic & Medicinal Chemistry Letters 16(13), 3479-3483 (2006).
2.Naik, G.S., and Tyagi, M.G. A pharmacological profile of ribavirin and monitoring of its plasma concentration in chronic hepatitis C infection. J.Clin.Exp.Hepatol. 2, 42-54 (2012).
3.Borden, K.L.B., and Culjkovic-Kraljacic, B. Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond? Leukemia and Lymphoma 51(10), 1805-1815 (2010).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 408.2 |
| 分子式 | C10H11N4O9P • 2Na |
| CAS号 | 25899-70-1 |
| 稳定性 | ≥ 2 years |
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