CYM 5520
货号：
17638-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 17638-1mg |
| 描述 | Sphingosine-1-phosphate (S1P; Item No. 62570) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P2 has been implicated in multiple biological functions, including Rho activation, inhibition of Rac and cell migration, and in “feed forward” autocrine signaling in NF-κB survival signaling of tumor cells.1 CYM 5520 is a noncompetitive allosteric agonist of S1P2(EC50 = 0.48 μM) that does not display agonist activity towards S1P1, S1P3, S1P4, or S1P5.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Satsu, H.,Schaeffer, M.T.,Guerrero, M., et al. A sphingosine 1-phosphate receptor 2 selective allosteric agonist. Bioorganic & Medicinal Chemistry 21(17), 5373-5382 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 345.4 |
| 分子式 | C21H19N3O2 |
| CAS号 | 1449747-00-5 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
