| 货号 | 17564-10mg |
| 描述 | Isoxanthopterin is a natural intermediate in the pteridine pathway, which has roles in pigmentation and cell division.1 It can be produced naturally from 7-oxobiopterin or in vitro by the oxidation of pterin by xanthine oxidase.1,2 Isoxanthopterin is a guanine analog that interferes with RNA and DNA synthesis and can inhibit cell proliferation.3,4 Methylated derivatives of isoxanthopterin are fluorescent guanine analogs that are used to study DNA structure.3,5 |
| 别名 | NSC 118090;NSC 614991; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Ziegler, I.,McDonaldo, T.,Hesslinger, C., et al. Development of the pteridine pathway in the zebrafish, Danio rerio. The Journal of Biological Chemisty 275(25), 18926-18932 (2000). 2.Neubert, P.,Besenfelder, E., and Koch, K. Enzymatic inhibition assay for fluorometric determination of allopurinol and oxipurinol in serum and urine. Arzneimittel-Forschung 30(11), 1857-1859 (1980). 3.Lagowski, J.M., and Forrest, H.S. Interaction in vitro between isoxanthopterin and DNA. Proceedings of the National Academy of Sciences of the United States of America 58(4), 1541-1547 (1967). 4.Ziegler, I.,Hamm, U., and Berndt, J. Participation of pterins in the control of lymphocyte stimulation and lymphoblast proliferation. Cancer Research 43, 5356-5359 (1983). 5.Widom, J.R.,Rappoport, D.,Perdomo-Ortiz, A., et al. Electronic transition moments of 6-methyl isoxanthopterin--a fluorescent analogue of the nucleic acid base guanine. Nucleic Acids Research 41(2), 995-1004 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 179.1 |
| 分子式 | C6H5N5O2 |
| CAS号 | 529-69-1 |
| 稳定性 | ≥ 2 years |
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