Trimethylamine N-oxide
货号：
17354-500mg 基本售价：
350.0 元 规格：
500 mg
产品信息
概述| 货号 | 17354-500mg |
| 描述 | Trimethylamine N-oxide (TMAO) is a product of the oxidation of TMA by flavin-containing mono-oxygenase 3 in the liver.1 TMAO levels predict risk for atherosclerosis and are elevated in patients with chronic kidney disease and obesity.1,2 TMAO levels are decreased in ulcerative colitis.1 TMAO increases atherosclerosis in ApoE-/- mice, suggesting that TMAO can directly induce cardiovascular disease.1 The biosynthesis of TMA is dependent on gut bacteria, providing a link between the biome and cardiovascular disease.1,2 |
| 别名 | NSC 408426;TMAO; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhang, L.S., and Davies, S.S. Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions. Genome Med. 8(1), 46 (2016).
2.Velasquez, M.T.,Ramezani, A.,Manal, A., et al. Trimethylamine N-oxide: The good, the bad and the unknown. Toxins (Basel) 8(11), E326 (2016).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 75.1 |
| 分子式 | C3H9NO |
| CAS号 | 1184-78-7 |
| 稳定性 | ≥ 2 years |
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