Amoxapine
货号：
17347-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 17347-100mg |
| 描述 | Amoxapine is a tetracyclic antidepressant with a wide range of pharmacological effects. It inhibits norepinephrine and serotonin reuptake, binding the respective transporters with Kd values of 16 and 58 nM.1 It has also been shown to act as either an antagonist or inverse agonist at serotonin 5-HT2A,2B,2C,3,6,7(Kis = 1 and 2 nM for 5-HT2A and 5-HT2C, respectively), dopamine D2,3,4(Kd = 160 nM for D2), α1-adrenergic (Kd = 50 nM), and histamine H1(Kd = 25 nM) receptors.2,3 |
| 别名 | CL-67772; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tatsumi, M.,Groshan, K.,Blakely, R.D., et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. European Journal of Pharmacology 340(2-3), 249-258 (1997).
2.Pälvimäki, E.P.,Roth, B.L.,Majasuo, H., et al. Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2C receptor. Psychopharmacology (Berl) 126(3), 234-240 (1996).
3.Richelson, E., and Nelson, A. Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. Journal of Pharmacology and Experimental Therapeutics 230(1), 94-102 (1984).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 313.8 |
| 分子式 | C17H16ClN3O |
| CAS号 | 14028-44-5 |
| 稳定性 | ≥ 2 years |
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