Oxcarbazepine
货号：
17340-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 17340-10mg |
| 描述 | Oxcarbazepine was developed by structural variation of carbamazepine (Item No. 15422) for use as an anticonvulsant and mood stabilizing therapeutic for neuropathic pain, epilepsy, and affective disorders.1 In humans, oxcarbazepine is rapidly converted to an active metabolite, 10-hydroxycarbazepine, which then functions to inhibit both voltage-dependent sodium and voltage-dependent calcium channels, while potentiating voltage-dependent potassium channels.1,2 Oxcarbazepine also antagonizes adenosine A1 receptors, stimulates dopaminergic transmission, and inhibits glutamate release.1 |
| 别名 | GP47680; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ambrósio, A.F.,Soares-Da-Silva, P.,Carvalho, C.M., et al. Mechanisms of action of carbamazepine and its derivatives, oxcarbazepine, BIA 2-093, and BIA 2-024. Neurochemical Research 27(1-2), 121-130 (2002).
2.Macdonald, R.L., and Kelly, K.M. Antiepileptic drug mechanisms of action. Epilepsia 36(Suppl 2), S2-S12 (1995).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 252.3 |
| 分子式 | C15H12N2O2 |
| CAS号 | 28721-07-5 |
| 稳定性 | ≥ 2 years |
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