| 货号 | 17333-1mg |
| 描述 | Temoporfin is a synthetic chlorin with light-activated actions. When administered systemically, temoporfin accumulates in tumor cells.1,2 When stimulated with light (650-652 nm) in the presence of oxygen, reactive oxygen species are generated, leading to necrosis within the tumor.1,2 Different approaches to using photodynamic therapy with temoporfin in palliative care are currently of interest.3,4 |
| 别名 | Foscan;KW 2345;m-THPC; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Alian, W.,Andersson-Engels, S.,Svanberg, K., et al. Laser-induced fluorescence studies of meso-tetra(hydroxyphenyl)chlorin in malignant and normal tissues in rats. British Journal of Cancer 70(5), 880-885 (1994). 2.Ris, H.B.,Altermatt, H.J.,Inderbitzi, R., et al. Photodynamic therapy with chlorins for diffuse malignant mesothelioma: Initial clinical results. British Journal of Cancer 64(6), 1116-1120 (1991). 3.Reshetov, V.,Lassalle, H.P.,François, A., et al. Photodynamic therapy with conventional and PEGylated liposomal formulations of mTHPC (temoporfin): Comparison of treatment efficacy and distribution characteristics in vivo. Int.J.Nanomedicine 8, 3817-3831 (2013). 4.Succo, G.,Rosso, S.,Fadda, G.L., et al. Salvage photodynamic therapy for recurrent nasopharyngeal carcinoma. Photodiagnosis Photodyn.Ther. 11(2), 63-70 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 680.8 |
| 分子式 | C44H32N4O4 |
| CAS号 | 122341-38-2 |
| 稳定性 | ≥ 2 years |
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