Esomeprazole Magnesium
货号:
17326-10mg 基本售价:
350.0 元 规格:
10 mg
产品信息
概述货号 | 17326-10mg |
描述 | Esomeprazole, the (S)-enantiomer of omeprazole (Item No. 14880), is a selective inhibitor of the gastric H+/K+ATPase.1 It is highly effective at inhibiting gastric acid secretion and demonstrates lower first-pass hepatic metabolism and slower plasma clearance, resulting in increased bioavailability compared to omeprazole.1,2 Esomeprazole is predominantly metabolized by the cytochrome P450 (CYP) isomer CYP3A4.1 |
别名 | (S)-Omeprazole; |
性能供应商 | Cayman |
应用文献 |
1.Shi, S., and Klotz, U. Proton pump inhibitors: An update of their clinical use and pharmacokinetics. Eur. J. Clin. Pharmacol. 64, 935-951 (2008). 2.Lind, T.,Rydberg, L.,Kylebäck, A., et al. Esomeprazole provides improved acid control vs. omeprazole in patients with symptoms of gastro-oesophageal reflux disease. Alimentary Pharmacology and Therapeutics 14, 861-867 (2000).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 713.1 |
分子式 | C34H36MgN6O6S2 |
CAS号 | 161973-10-0 |
稳定性 | ≥ 2 years |
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