Solifenacin (succinate)
货号：
17320-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 17320-10mg |
| 描述 | Solifenacin is a competitive antagonist of muscarinic receptors that potently blocks signaling through M1, M2, and M3(Kis = 25, 125, and 10 nM, respectively).1,2 Through this action, solifenacin prevents activation by acetylcholine, resulting in muscle relaxation. Solifenacin is used in the management of overactive bladder, as it reduces the number of micturition, urgency, and incontinence episodes.1,2 |
| 别名 | Isoprenalinoe sulfate;YM-67905; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Hegde, S.S. Muscarinic receptors in the bladder: From basic research to therapeutics. Br. J. Pharmacol. 147(2), S80-S87 (2006).
2.Yamada, S.,Ito, Y., and Tsukada, H. α1-Adrenoceptors and muscarinic receptors in voiding function - binding characteristics of therapeutic agents in relation to the pharmacokinetics. Br. J. Clin. Pharmacol. 72(2), 205-217 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 480.6 |
| 分子式 | C23H26N2O2 • C4H6O4 |
| CAS号 | 242478-38-2 |
| 稳定性 | ≥ 2 years |
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