| 货号 | 17315-10mg |
| 描述 | Telithromycin is a ketolide antibiotic that, like the related macrolides, binds bacterial ribosomes to inhibit translation as well as block ribosome subunit assembly.1,2 It has good activity in vitro against the most common community-acquired respiratory tract pathogens, including S. pneumoniae,H. influenzae,M. catarrhalis, and S. pyogenes.3,4 Telithromycin is also effective against atypical and intracellular respiratory tract bacterial pathogens, such as Mycoplasma,Legionella, and Chlamydia.4 |
| 别名 | HMR 3647;Ketek;RU 66647; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Hansen, L.H.,Mauvais, P., and Douthwaite, S. The macrolide-ketolide antibiotic binding site is formed by structures in domains II and V of 23S ribosomal RNA. Molecular Microbiology 31(2), 623-631 (1999). 2.Douthwaite, S., and Champney, W.S. Structures of ketolides and macrolides determine their mode of interaction with the ribosomal target site. Journal of Antimicrobial Chemotherapy 48 (Topic T1), 1-8 (2001). 3.Felmingham, D.,Zhanel, G., and Hoban, D. Activity of the ketolide antibacterial telithromycin against typical community-acquired respiratory pathogens. Journal of Antimicrobial Chemotherapy 48(Topic T1), 33-42 (2001). 4.Hammerschlag, M.R.,Roblin, P.M., and Bébéar, C.M. Activity of telithromycin, a new ketolide antibacterial, against atypical and intracellular respiratory tract pathogens. J. Antimicrob. Chemother. 48(Topic T1), 25-31 (2001). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 812 |
| 分子式 | C43H65N5O10 |
| CAS号 | 191114-48-4 |
| 稳定性 | ≥ 2 years |
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