| 货号 | 17251-1mg |
| 描述 | m-3M3FBS (Item No. 16867) is an activator of phospholipase C (PLC) that stimulates superoxide generation, cytoplasmic calcium increase, and inositol phosphate formation in humans.1 It is used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122 (Item No. 70740).2,3,4o-3M3FBS is an inactive analog of m-3M3FBS that can be used as a negative control.1 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Bae, Y.S.,Lee, T.G.,Park, J.C., et al. Identification of a compound that directly stimulates phospholipase C activity. Molecular Pharmacology 63(5), 1043-1050 (2003). 2.Kim, S.D.,Kim, H.J.,Shim, J.W., et al. Phospholipase C activator m-3M3FBS protects against morbidity and mortality associated with sepsis. Journal of Immunology 189(4), 2000-2005 (2012). 3.Semple-Rowland, S.,Madorsky, I.,Bolch, S., et al. Activation of phospholipase C mimics the phase shifting effects of light on melatonin rhythms in retinal photoreceptors. PLoS One 8(12), 1-7 (2013). 4.Szebenyi, S.A.,Ogura, T.,Sathyanesan, A., et al. Increases in intracellular calcium via activation of potentially multiple phospholipase C isozymes in mouse olfactory neurons. Front.Cell.Neurosci. 8, 1-14 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 343.4 |
| 分子式 | C16H16F3NO2S |
| CAS号 | 313981-55-4 |
| 稳定性 | ≥ 2 years |
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