Sanguinarine (chloride)
货号：
16951-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 16951-1mg |
| 描述 | Sanguinarine is a benzylisoquinoline alkaloid isolated from plants belonging to the family Papaveraceae.1 It exhibits antimicrobial, anti-inflammatory, and anti-oxidant properties and demonstrates antiproliferative and pro-apoptotic effects in some cancer cell lines. Sanguinarine suppresses NF-κB activation by blocking the degradation of IκBα and sensitizes cancer cells to apoptosis by inducing ROS generation and activating TNF-related apoptosis-inducing ligand.2 Furthermore, sanguinarine has been shown to reduce cancer cell metastasis though the inhibition of MMP-2 and MMP-9 activation and to exhibit antiangiogenic activity by downregulating VEGF-induced Akt activation.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ziegler, J., and Facchini, P.J. Alkaloid biosynthesis: Metabolism and trafficking. Annu.Rev.Plant Biol. 59, 735-769 (2008).
2.Gupta, S.C.,Kim, J.H.,Prasad, S., et al. Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals. Cancer Metastasis Reviews 29(3), 405-434 (2010).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 367.8 |
| 分子式 | C20H14NO4 • Cl |
| CAS号 | 5578-73-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
