Allopregnanolone
货号：
16930-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 16930-1mg |
| 描述 | Allopregnanolone is an endogenous inhibitory pregnane neurosteroid that is synthesized from progesterone (Item No. 15876).1 It acts as a positive allosteric modulator of GABAA receptors at nM concentrations (exhibiting the greatest potentiation at isoforms containing δ subunits) and of GABAC receptors at µM concentrations.1 Allopregnanolone displays effects similar to other GABAA receptor potentiators such as benzodiazepines, including potent anticonvulsant, anxiolytic, and sedative activity.1,2 |
| 别名 | ALLO;3α,5α-tetrahydro Progesterone;3α,5α-THP; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Reddy, D.S. Neurosteroids: Endogenous role in the human brain and therapeutic potentials. Progress in Brain Research 186, 113-137 (2010).
2.Johnston, G.A.R.,Chebib, M.,Hanrahan, J.R., et al. Neurochemicals for the investigation of GABAC receptors. Neurochemical Research 35(12), 1970-1977 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 318.5 |
| 分子式 | C21H34O2 |
| CAS号 | 516-54-1 |
| 稳定性 | ≥ 2 years |
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