Pyr3
货号：
16888-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 16888-1mg |
| 描述 | Pyr3 is a pyrazole compound that selectively antagonizes the transient receptor potential canonical channel 3 (TRPC3).1 It inhibits TRPC3-mediated Ca2+ influx with an IC50 value of 0.7 μM without effect on other TRPC members and suppresses activation of nuclear factor of activated T cells with an IC50 value of 0.05 μM.1 Pyr3 has been shown to suppress cardiac hypertrophy in mice at 0.1 mg/kg/day.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Kiyonaka, S.,Kato, K.,Nishida, M., et al. Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound. Proceedings of the National Academy of Sciences of the United States of America 106(13), 5400-5405 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 456.6 |
| 分子式 | C16H11Cl3F3N3O3 |
| CAS号 | 1160514-60-2 |
| 稳定性 | ≥ 2 years |
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