| 货号 | 16807-100mg |
| 描述 | (S)-(+)-Methoprene is a widely-used insect growth regulator.1 It is remarkable for its lack of significant effects against a wide variety of mammals, although concerns remain for its effects on arthropod development.1,2 Methoprene acts as an activator of the juvenile hormone receptor, known as Methoprene-tolerant or Met (Kd = 12.3 nM).3,4 Met is a transcription factor that, upon activation with juvenile hormone or methoprene, regulates gene expression that inhibits metamorphosis.5 |
| 别名 | Altosid™;d-Methoprene;ZR 2458; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Siddall, J.B. Insect growth regulators and insect control: A critical appraisal. Environmental Health Perspectives 14, 119-126 (1976). 2.Wright, J.E. Environmental and toxicological aspects of insect growth regulators. Environmental Health Perspectives 14, 127-132 (1976). 3.Charles, J.P.,Iwema, T.,Epa, V.C., et al. Ligand-binding properties of a juvenile hormone receptor, methoprene-tolerant. Proceedings of the National Academy of Sciences of the United States of America 108(52), 21128-21133 (2011). 4.Osir, E.O., and Riddiford, L.M. Nuclear binding sites for juvenile hormone and its analogs in the epidermis of the tobacco hornworm. The Journal of Biological Chemisty 263(27), 13812-13818 (1988). 5.Zou, Z.,Saha, T.T.,Roy, S., et al. Juvenile hormone and its receptor, methoprene-tolerant, control the dynamics of mosquito gene expression. Proceedings of the National Academy of Sciences of the United States of America 110(24), E2173-E2181 (2013). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 310.5 |
| 分子式 | C19H34O3 |
| CAS号 | 65733-16-6 |
| 稳定性 | ≥ 2 years |
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