Fudosteine
货号：
16722-10mg 基本售价：
350.0 元 规格：
10 mg
产品信息
概述| 货号 | 16722-10mg |
| 描述 | Fudosteine is a cysteine derivative that interferes with the increase in goblet cell number, expression of the mucin MUC5AC, and subsequent mucin secretion, in airways agonized with tobacco smoke, isoproterenol, lipopolysaccharide, TNF-α, or oxidants.1,2,3 Fudosteine, which is a thiol compound with antioxidant properties, limits NF-κB signaling and reduces inflammatory gene expression.3 It has greater bioavailability than N-acetyl-cysteine and increases cysteine levels in cells.3 |
| 别名 | SS320A; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Takahashi, K.,Mizuno, H.,Ohno, H., et al. Effects of SS320A, a new cysteine derivative, on the change in the number of goblet cells induced by isoproterenol in rat tracheal epithelium. Japanese Journal of Pharmacology 77(1), 71-77 (1998).
2.Rhee, C.K.,Kang, C.M.,You, M.B., et al. Effect of fudosteine on mucin production. European Respiratory Journal 32(5), 1195-1202 (2008).
3.Rahman, I. Pharmacological antioxidant strategies as therapeutic interventions for COPD. Biochimica et Biophysica Acta 1822(5), 714-728 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 179.2 |
| 分子式 | C6H13NO3S |
| CAS号 | 13189-98-5 |
| 稳定性 | ≥ 2 years |
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