| 货号 | 16673-100mg |
| 描述 | L-(-)-Norepinephrine is a natural neurotransmitter and hormone that is biosynthesized from dopamine by dopamine β-hydroxylase.1,2 It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for α1, α2, and β1 adrenoceptors, respectively).2 Through these receptors, L-(-)-norepinephrine regulates diverse processes, including those in neurological, immunological, and vascular systems.2,3,4,5 |
| 别名 | Arterenol;Levarterenol;NE;L-Noradrenaline; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Gannon, M.,Che, P.,Chen, Y., et al. Noradrenergic dysfunction in Alzheimer’s disease. Frontiers in Neuroscience 9, 1-12 (2015). 2.Ramos, B.P. and Arnsten, A.F.T. Adrenergic pharmacology and cognition: Focus on the prefrontal cortex. Pharmacology & Therapeutics 113(3), 523-536 (2007). 3.Lorton, D. and Bellinger, D.L. Molecular mechanisms underlying β-adrenergic receptor-mediated cross-talk between sympathetic neurons and immune cells. International Journal of Molecular Sciences 16, 5635-5665 (2015). 4.Nance, D.M. and Sanders, V.M. Autonomic innervation and regulation of the immune system (1987-2007). Brain Behav.Immun. 21(6), 736-745 (2007). 5.Raiteri, M. Functional pharmacology in human brain. Pharmacological Reviews 58(2), 162-193 (2006). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 337.3 |
| 分子式 | C8H11NO3 • C4H6O6 • H2O |
| CAS号 | 108341-18-0 |
| 稳定性 | ≥ 2 years |
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