| 货号 | 16169-1g |
| 描述 | 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.1,2,3 The circular arrangement of its glucose units produces a torus-shaped ring configuration in which the CH2 groups and ether linkages of the molecule face the hollow interior, resulting in a nonpolar, hydrophobic cavity and a polar, hydrophilic exterior. When combined in solution with other compounds, the nonpolar aromatic portions of that compound interact with the nonpolar interior of the HP-β-CD molecule, thus isolating the aromatic portion of the molecule from the water and thereby increasing its aqueous solubility.1,4 |
| 别名 | HP-β-CD; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Katageri, A.R. and Sheikh, M.A. Cyclodextrin a gift to pharmaceutical world review. International Research Journal of Pharmacy 3(1), 52-56 (2012). 2.Shewale, B.D.,Sapkal, N.P.,Raut, N.A., et al. Effect of hydroxylpropyl-β-cyclodextrin on solubility of carvedilol. Indian J.Pharm.Sci. 70(2), 255-257 (2008). 3.Loftsson, T.,Jansook, P. and Stefánsson, E. Topical drug delivery to the eye: Dorzolamide. Acta.Ophthalmol. 90, 603-608 (2012). 4.Rao, V.M.,Nerurkar, M.,Pinnamaneni, S., et al. Co-solubilization of poorly soluble drugs by micellization and complexation. International Journal of Pharmacy 319, 98-106 (2006). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | 22 |
| 纯度 | ≥95% |
| 计算分子量 | 1541.6 |
| 分子式 | (C6H9O5)7(C3H7O) |
| CAS号 | 128446-35-5 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |