1-Aminocyclopropanecarboxylic Acid
货号：
16132-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 16132-100mg |
| 描述 | 1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence.1 ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 µM) in the presence of low levels (1 µM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 µM) of glutamate.2 This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.2 |
| 别名 | ACC;ACPC;NSC 98430; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bleecker, A.B. and Kende, H. Ethylene: A gaseous signal molecule in plants. Annual Reviews of Cell Development and Biology 16, 1-18 (2000).
2.Nahum-Levy, R.,Fossom, L.H.,Skolnick, P., et al. Putative partial agonist 1-aminocyclopropanecarboxylic acid acts concurrently as a glycine-site agonist and a glutamate-site antagonist at N-methyl-D-aspartate receptors. Molecular Pharmacology 56(6), 1207-1218 (1999).
|
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 101.1 |
| 分子式 | C4H7NO2 |
| CAS号 | 22059-21-8 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
