Edrophonium (chloride)
货号：
15928-100mg 基本售价：
350.0 元 规格：
100 mg
产品信息
概述| 货号 | 15928-100mg |
| 描述 | Edrophonium (chloride) is an acetylcholinesterase (AChE) inhibitor that is known to prevent the breakdown of the neurotransmitter acetylcholine by binding specifically to its catalytic site.1 It has been shown to inhibit AChE activity in human red blood cells, purified calf forebrain, and purified octopus brain with Ki values of 0.2, 0.2, and 0.4 µM, respectively.2 Edrophonium is often used as part of a battery of pharmacological tests to confirm a diagnosis of the autoimmune neuromuscular junction disorder, myasthenia gravis.3 |
| 别名 | Enlon®;Tensilon®; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Roufogalis, B.D. and Wickson, V.M. Acetylcholinesterase: specificity of the peripheral anionic site for cholinergic ligands. Molecular Pharmaceutics 11, 352-360 (2011).
2.Boyle, N.A.,Talesa, V.,Giovannini, E., et al. Synthesis and study of thiocarbonate derivatives of choline as potential inhibitors of acetylcholinesterase. Journal of Medicinal Chemistry 40(19), 3009-3013 (1997).
3.Juel, V.C. and Massey, J.M. Myasthenia gravis. Orphanet Journal of Rare Diseases 2, 44 (2007).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 201.7 |
| 分子式 | C10H16NO • Cl |
| CAS号 | 116-38-1 |
| 稳定性 | ≥ 2 years |
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