Imipramine (hydrochloride)
货号:
15890-1g 基本售价:
350.0 元 规格:
1 g
产品信息
概述货号 | 15890-1g |
描述 | Imipramine is a first generation tricyclic antidepressant that acts primarily as an inhibitor of serotonin and norepinephrine transporters (Kds = 1.4 and 37 nM, respectively).1,2 It also is an antagonist at histamine, muscarinic acetylcholine, and α1-adrenergic receptors (Kd values are 37, 46, and 32 nM for H1, M1, and α1, respectively).3 |
别名 | Melipramine;Tofranil; |
性能供应商 | Cayman |
应用文献 |
1.Spencer, P.S. Review of the pharmacology of existing antidepressants. British Journal of Clinical Pharmacology 4(Suppl 2), 57S-68S (1977). 2.Tatsumi, M.,Groshan, K.,Blakely, R.D., et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. European Journal of Pharmacology 340(2-3), 249-258 (1997). 3.Cusack, B.,Nelson, A. and Richelson, E. Binding of antidepressants to human brain receptors: Focus on newer generation compounds. Psychopharmacology (Berl) 114(4), 559-565 (1994).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 316.9 |
分子式 | C19H24N2 • HCl |
CAS号 | 113-52-0 |
稳定性 | ≥ 2 years |
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