Daptomycin
货号：
15615-5mg 基本售价：
350.0 元 规格：
5 mg
产品信息
概述| 货号 | 15615-5mg |
| 描述 | Daptomycin is a naturally occurring cyclic lipopeptide produced by the soil saprotroph S. roseosporus that is effective against resistant Gram-positive bacteria (MIC90s range from 0.25-16 mg/L).1,2 It binds to bacterial plasma membranes to disrupt multiple aspects of function, including altering membrane potential and redirecting proteins essential for cell division and cell wall synthesis.2,3 |
| 别名 | Cubicin®;LY146032; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tally, F.P. and DeBruin, M.F. Development of daptomycin for Gram-positive infections. Journal of Antimicrobial Chemotherapy 46(4), 523-526 (2000).
2.Steenbergen, J.N.,Alder, J.,Throne, G.M., et al. Daptomycin: A lipopeptide antibiotic for the treatment of serious Gram-positive infections. Journal of Antimicrobial Chemotherapy 55(3), 283-288 (2005).
3.Pogliano, J.,Pogliano, N. and Silverman, J.A. Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins. Journal of Bacteriology 194(17), 4494-4504 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 1620.7 |
| 分子式 | C72H101N17O26 |
| CAS号 | 103060-53-3 |
| 稳定性 | ≥ 2 years |
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