N-tert-butyl-α-Phenylnitrone
货号：
15412-500mg 基本售价：
350.0 元 规格：
500 mg
产品信息
概述| 货号 | 15412-500mg |
| 描述 | N-tert-butyl-α-Phenylnitrone (PBN) is a cell permeable spin trap commonly used in free radical research.1 It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects.2 At millimolar concentrations, PBN has been shown to inhibit LPS-induced NF-κB DNA binding activity and inhibits COX-2 catalytic activity.3 |
| 别名 | PBN; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Haseloff, R.F.,Mertsch, K.,Rohde, E., et al. Cytotoxicity of spin trapping compounds. FEBS Letters 418, 73-75 (1997).
2.Floyd, R.A. Antioxidants, oxidative stress, and degenerative neurological disorders. Proceedings of the Society for Experimental Biology and Medicine 222, 236-245 (1999).
3.Kotake, Y.,Sang, H.,Miyajima, T., et al. Inhibition of NF-κB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN). Biochimica et Biophysica Acta 1448, 77-84 (1998).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 177.3 |
| 分子式 | C11H15NO |
| CAS号 | 3376-24-7 |
| 稳定性 | ≥ 2 years |
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