NS 11021
货号：
15347-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 15347-1mg |
| 描述 | NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1).1 It is selective for BKCa and is thought to bind directly the ɑ subunit.1 NS 11021 has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro and to enhance erectile responses in intact rats.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bentzen, B.H.,Nardi, A.,Calloe, K., et al. The small molecule NS11021 is a potent and specific activator of Ca2+-activated big-conductance K+ channels. Mol. Pharmacol. 72(4), 1033-1044 (2007).
2.Kun, A.,Matchkov, V.V.,Stankevicius, E., et al. NS11021, a novel opener of large-conductance Ca(2+)-activated K(+) channels, enhances erectile responses in rats. Br. J. Pharmacol. 158(6), 1465-1476 (2009).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 511.2 |
| 分子式 | C16H9BrF6N6S |
| CAS号 | 956014-19-0 |
| 稳定性 | ≥ 2 years |
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