货号 | 15330-1mg |
描述 | Ginsenosides are pharmacologically active natural constituents of ginseng and other plants of the genus Panax.1 Structurally, they are steroid glycosides derived from the triterpene squalene.1 Ginsenoside Re is a panaxatriol saponin that is more abundant in some Panax species (e.g.,P. quinquefolium) than others.2 This ginsenoside has diverse in vitroandin vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.2,3,4,5 Ginsenoside Re improves the effectiveness of chemotherapeutic agents by decreasing the expression of Multidrug Resistance Protein 1 and inhibiting P-glycoprotein.6 Notably, this ginsenoside is converted to other forms in response to steaming or heating plant materials, leading to loss of activity.2 |
别名 | Chikusetsusaponin IVc;NSC 308877;Panaxoside Re;Sanchinoside Re; |
供应商 | Cayman |
应用文献 | |
1.Liang, Y. and Zhao, S. Progress in understanding of ginsenoside biosynthesis. Plant Biol.(Stuttg) 10(4), 415-421 (2008). 2.Chen, C.F.,Chiou, W.F. and Zhang, J.T. Comparison of the pharmacological effects of Panax ginseng and Panax quinquefolium. Acta.Pharmacol.Sin. 29(9), 1103-1108 (2008). 3.Peng, D.,Wang, H.,Qu, C., et al. Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics. Chin.Med. 7, 2 (2012). 4.Han, D.H.,Kim, S.H.,Higashida, K., et al. Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats. Metabolism 61(11), 1615-1621 (2012). 5.Gao, Y.,Yang, M.F.,Su, Y.P., et al. Ginsenoside Re reduces insulin resistance through activation of PPAR-γ pathway and inhibition of TNF-α production. Journal of Ethnopharmacology 147(2), 509-516 (2013). 6.Helms, S. Cancer prevention and therapeutics: Panax ginseng. Altern.Med.Rev. 9(3), 259-274 (2004). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 947.2 |
分子式 | C48H82O18 |
CAS号 | 52286-59-6 |
稳定性 | ≥ 2 years |
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