MoTP
货号：
15204-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 15204-1mg |
| 描述 | MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration.1,2 MoTP is converted to a cytotoxin in cells with high tyrosinase activity, which in the zebrafish embryo are limited to melanoblasts and newly formed melanocytes.3 The wash-out of MoTP allows regeneration through the proliferation of melanocyte stem cells.3,2 |
| 别名 | 4-(4-Morpholinylbutylthio)phenol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yang, C.T. and Johnson, S.L. Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes. Development 133(18), 3563-3573 (2006).
2.Yang, C.T.,Hindes, A.E.,Hultman, K.A., et al. Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish. PLoS Genetics 3(6), e88 (2007).
3.Hultman, K.A.,Budi, E.H.,Teasley, D.C., et al. Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes. PLoS Genetics 5(7), e1000544 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 267.4 |
| 分子式 | C14H21NO2S |
| CAS号 | 57055-82-0 |
| 稳定性 | ≥ 2 years |
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