ML-161
货号：
15179-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 15179-1mg |
| 描述 | ML-161 is an allosteric, reversible inhibitor of proteinase-activated receptor 1 (PAR1) on platelets, preventing surface expression of P-selectin induced by the peptide SFLLRN with an IC50 value of 0.26 µM.1 It blocks platelet activation induced by thrombin as well as by SFLLRN but not by PMA (Item No. 10008014), U-46619 (Item No. 16450), or collagen.1 |
| 别名 | AG-670;CID-1048267; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Dockendorff, C.,Aisiku, O.,VerPlank, L., et al. Discovery of 1,3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor. ACS Med.Chem.Lett. 3(3), 232-237 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 361.2 |
| 分子式 | C17H17BrN2O2 |
| CAS号 | 423735-93-7 |
| 稳定性 | ≥ 2 years |
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