Omeprazole
货号：
14880-25mg 基本售价：
350.0 元 规格：
25 mg
产品信息
概述| 货号 | 14880-25mg |
| 描述 | Omeprazole is a selective and irreversible inhibitor of the gastric H+/K+ ATPase pump (IC50 = 1.1 μM).1 It is a racemic mixture of two enantiomers, S-omeprazole (esomeprazole) and R-omeprazil, which are prodrugs of the active sulfonamide which is formed by acid-stimulated conversion.2,3 Both enantiomers are extensively metabolized by the cytochrome P450 (CYP) isomers CYP2C19 and CYP3A4.3 |
| 别名 | OMEP;OMP;OMZ; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Smolka, A.J.,Goldenring, J.R.,Gupta, S., et al. Inhibition of gastric H,K-ATPase activity and gastric epithelial cell IL-8 secretion by the pyrrolizine derivative ML 3000. BMC Gastroenterol. 4(4), 1-11 (2004).
2.Richardson, P.,Hawkey, C.J. and Stack, W.A. Proton pump inhibitors. Pharmacology and rationale for use in gastrointestinal disorders. Drugs 56(3), 307-335 (1998).
3.Shi, S. and Klotz, U. Proton pump inhibitors: An update of their clinical use and pharmacokinetics. Eur. J. Clin. Pharmacol. 64, 935-951 (2008).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 345.4 |
| 分子式 | C17H19N3O3S |
| CAS号 | 73590-58-6 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
