Citicoline (sodium salt)
货号：
14629-50mg 基本售价：
350.0 元 规格：
50 mg
产品信息
概述| 货号 | 14629-50mg |
| 描述 | Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine, the major phospholipid in eukaryotic cells.1 It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicholine demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders.2 Exogenous administration of citicholine to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.3 |
| 别名 | Cytidine 5-diphosphocholine;Flussorex;Gerolin;Logan;Neurotron;Sinkron; |
性能| 供应商 | Cayman |
| 应用文献 |
1.McMaster, C.R. and Bell, R.M. Phosphatidylcholine biosynthesis via the CDP-choline pathway in Saccharomyces cerevisiae. The Journal of Biological Chemisty 269(20), 14776-14783 (1994).
2.Dávalos, A. and Secades, J. Citicoline preclinical and clinical update 2009-2010. Stroke 42(1), 36-39 (2011).
3.Rao, M.,Hatcher, J.F. and Dempsey, R.J. Lipid alterations in transient forebrain ischemia: Possible new mechanisms of CDP-choline neuroprotection. Journal of Neurochemistry 75(6), 2528-2535 (2000).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 510.3 |
| 分子式 | C14H25N4O11P2 • Na |
| CAS号 | 33818-15-4 |
| 稳定性 | ≥ 2 years |
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