Sumatriptan (succinate)
货号：
14600-5mg 基本售价：
350.0 元 规格：
5 mg
产品信息
概述| 货号 | 14600-5mg |
| 描述 | Sumatriptan (succinate) is a serotonin 5-hydroxytryptamine 1 (5-HT1) receptor agonist with selective affinity for 5-HT1B and 5-HT1D receptors with IC50 values of 9.3 and 7.3 nM, respectively.1 It also has affinity for the 5-HT1F receptor (IC50 = 17.8 nM).1 Sumatriptan (succinate) has been shown to induce vasoconstriction of human middle meningeal arteries (EC50 = 89.9 nM) and reduce vascular inflammation associated with migraines.1 |
| 别名 | GR 43175C;Imigran;Imitrex; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Razzaque, Z.,Heald, M.A.,Pickard, J.D., et al. Vasoconstriction in human isolated middle meningeal arteries: Determining the contribution of 5-HT1B- and 5-HT1F-receptor activation. British Journal of Clinical Pharmacology 47(1), 75-82 (1999).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 413.5 |
| 分子式 | C14H21N3O2S • C4H6O4 |
| CAS号 | 103628-48-4 |
| 稳定性 | ≥ 2 years |
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