8-bromo-Cyclic AMP (sodium salt)
货号:
14431-5mg 基本售价:
350.0 元 规格:
5 mg
产品信息
概述货号 | 14431-5mg |
描述 | 8-bromo-Cyclic AMP (8-bromo-cAMP) is a cell permeable analog of cAMP that activates cyclic-AMP-dependent protein kinase with a Ka value of 0.05 μM.1 It activates cyclic-GMP- dependent protein kinase with 100-fold reduced potency (Ka = 5.8 μM).1 8-bromo-cAMP is more stable to hydrolysis and has increased membrane permeability compared to unmodified cAMP.1 |
别名 | 8-Bromoadenosine 3,5-cyclic monophosphate;8-bromo-cAMP (sodium salt); |
性能供应商 | Cayman |
应用文献 |
1.Sandberg, M.,Butt, E.,Nolte, C., et al. Characterization of Sp-5,6-dichloro-1-β-D-ribofuranosylbenzimidazole-3,5-monophosphorothioate (Sp-5,6-DCl-cBiMPS) as a potent and specific activator of cyclic-AMP-dependent protein kinase in cell extracts and intact cells. Biochemistry Journal 279, 521-527 (1991).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 430.1 |
分子式 | C10H10BrN5O6P • Na |
CAS号 | 76939-46-3 |
稳定性 | ≥ 2 years |
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