Ciprofloxacin (hydrochloride)
货号：
14286-5g 基本售价：
350.0 元 规格：
5 g
产品信息
概述| 货号 | 14286-5g |
| 描述 | Ciprofloxacin is a fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent.1 Its range of activity includes most strains of bacterial pathogens capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication.2 Most recently ciprofloxacin has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters.1,3 |
| 别名 | BAY-o 9867;NSC 620634; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Fukumoto, R.,Cary, L.H.,Gorbunov, N.V., et al. Ciprofloxacin modulates cytokine/chemokine profile in serum, improves bone marrow repopulation, and limits apoptosis and autophagy in ileum after whole body ionizing irradiation combined with skin-wound trauma. PLoS One 8(3), (2013).
2.Drlica, K. and Zhao, X. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiology and Molecular Biology Reviews 61(3), 377-392 (1997).
3.Meyerhoff, A.,Albrecht, R.,Meyer, J.M., et al. US food and drug administration approval of ciprofloxacin hydrochloride for management of postexposure inhalational anthrax. Clinical Infectious Diseases 39, 303-308 (2004).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 367.8 |
| 分子式 | C17H18FN3O3 • HCl |
| CAS号 | 93107-08-5 |
| 稳定性 | ≥ 2 years |
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