| 货号 | 13849-1g |
| 描述 | Cyclophosphamide is a nitrogen mustard alkylating agent used in the treatment of cancers and autoimmune disorders.1,2 In cells with low levels of aldehyde dehydrogenase, cyclophosphamide acts as a prodrug since it is metabolized to the active compound phosphoramide mustard, which crosslinks with DNA and causes cell death.3,4 |
| 别名 | Endoxan; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Yildirim-Toruner, C. and Diamond, B. Current and novel therapeutics in the treatment of systemic lupus erythematosus. J. Allergy Clin. Immunol. 127(2), 303-314 (2011). 2.Appel, G.B. New and future therapies for lupus nephritis. Cleve. Clin. J. Med. 79(2), 134-140 (2012). 3.Ahmed, A.R. and Hombal, S.M. Cyclophosphamide (Cytoxan). A review on relevant pharmacology and clinical uses. J. Am. Acad. Dermatol. 11(6), 1115-1126 (1984). 4.Bischoff, P.L.,Holl, V.,Coelho, D., et al. Apoptosis at the interface of immunosuppressive and anticancer activities: The examples of two classes of chemical inducers, oxysterols and alkylating agents. Curr. Med. Chem. 7(7), 693-713 (2000). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 279.1 |
| 分子式 | C7H15Cl2N2O2P • H2O |
| CAS号 | 6055-19-2 |
| 稳定性 | ≥ 2 years |
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