Imatinib (mesylate)
货号：
13139-25mg 基本售价：
350.0 元 规格：
25 mg
产品信息
概述| 货号 | 13139-25mg |
| 描述 | Imatinib (mesylate) is a first generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GIST), and other cancers. It selectively targets certain tyrosine kinases, including c-ABL, platelet-derived growth factor receptor, and KIT.1,2 In CML, imatinib (mesylate) inhibits the oncoprotein BCR-ABL, the product of the Philadelphia chromosome gene fusion. |
| 别名 | CGP57148B;Gleevec;Glivec;STI-571; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Druker, B.J. Translation of the Philadelphia chromosome into therapy for CML. Blood 112, 4808-4817 (2008).
2.Müller, B.A. Imatinib and its successors-how modern chemistry has changed drug development. Current Pharmaceutical Design 15, 120-133 (2009).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 589.7 |
| 分子式 | C29H31N7O • CH4SO3 |
| CAS号 | 220127-57-1 |
| 稳定性 | ≥ 2 years |
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