Carboplatin
货号：
13112-25mg 基本售价：
350.0 元 规格：
25 mg
产品信息
概述| 货号 | 13112-25mg |
| 描述 | Carboplatin is a platinum-based antineoplastic agent that functions by forming DNA adducts specifically in cancer cells, preventing DNA replication and transcription which leads to cell death. It has cytotoxic effects in ovarian, lung, and other cancer cell lines (IC50s = 14-200 μM).1,2 Carboplatin has been widely studied in clinical settings both alone or in combination with other agents to treat various solid tumors.3 |
| 别名 | NSC 201345;NSC 241240;Paraplatin®;Ribocarbo-L; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Al-Eisawi, Z.,Beale, P.,Chan, C., et al. Carboplatin and oxaliplatin in sequenced combination with bortezomib in ovarian tumour models. J.Ovarian Res. 6(1), 78 (2013).
2.Groen, H.J.,Sleijfer, S.,Meijer, C., et al. Carboplatin- and cisplatin-induced potentiation of moderate-dose radiation cytotoxicity in human lung cancer cell lines. British Journal of Cancer 72(6), 1406-1411 (1995).
3.Lokich, J., and Anderson, N. Carboplatin versus cisplatin in solid tumors: An analysis of the literature. Annals of Oncology 9(1), 13-21 (1998).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 371.3 |
| 分子式 | C6H12N2O4Pt |
| CAS号 | 41575-94-4 |
| 稳定性 | ≥ 2 years |
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