RD162
货号：
13039-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 13039-1mg |
| 描述 | RD162 is a second-generation androgen receptor (AR) antagonist. It inhibits binding of 18F-FDHT to AR in human prostate cancer cells with an IC50 value of 30.9 nM.1 RD162 completely suppresses VCaP cell proliferation at 1 µM and induces apoptosis of VCaP cells at 10 µM. RD162 is bioavailable and reduces LNCaP/AR tumor growth in castrated male mice at a daily oral dose of 10 mg/kg.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tran, C.,Ouk, S.,Clegg, N.J., et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 324(5928), 787-790 (2009).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 476.4 |
| 分子式 | C22H16F4N4O2S |
| CAS号 | 915087-27-3 |
| 稳定性 | ≥ 2 years |
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