Olanzapine
货号：
11937-25mg 基本售价：
350.0 元 规格：
25 mg
产品信息
概述| 货号 | 11937-25mg |
| 描述 | Olanzapine is an antipsychotic, thienobenzodiazepine compound that has been approved for use in the treatment of schizophrenia and bipolar disorder (formulated for human use under the name Zyprexa®). Olanzapine binds as an antagonist/inverse agonist to dopamine D1(Ki = 31 nM), dopamine D2(Ki = 11 nM), dopamine D4(Ki = 27 nM), serotonin 5-HT2A(Ki = 4 nM), serotonin 5-HT2C(Ki = 11 nM), serotonin 5-HT3(Ki = 57 nM), muscarinic M1(Ki = 2 nM), α1-adrenergic (Ki = 19 nM), and histamine H1(Ki = 7 nM) receptors.1 Olanzapine has a high affinity for dopamine D1 and D2 receptors (IC50s = 25 and 10 nM, respectively) in human striatal tissue and for 5-HT2A, 5-HT2C, muscarinic M1, and α1-adrenergic receptors (IC50s = 7, 71, 2, and 70 nM, respectively) in human frontal cortex.1 This product is intended for research purposes only. |
| 别名 | Zyprexa®; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bymaster, F.P.,Calligaro, D.O.,Falcone, J.F., et al. Radioreceptor binding profile of the atypical antipsychotic olanzapine. Neuropsychopharmacology 14(2), 87-96 (1996).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 312.4 |
| 分子式 | C17H20N4S |
| CAS号 | 132539-06-1 |
| 稳定性 | ≥ 2 years |
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