GQ-16
货号：
11908-5mg 基本售价：
350.0 元 规格：
5 mg
产品信息
概述| 货号 | 11908-5mg |
| 描述 | Full activation of peroxisome proliferator-activated receptor γ (PPARγ), e.g., using thiazolidinediones, effectively treats insulin resistance and type 2 diabetes but also commonly promotes weight gain, hyperphagia, and edema.1 GQ-16 is a partial agonist for PPARγ (Ki = 160 nM) which induces adipogenesis significantly less than the full activator rosiglitazone.1 Like rosiglitazone, GQ-16 reverses high fat diet-mediated impairments in insulin signaling.1 However, GQ-16 does not induce weight gain, hyperphagia, or edema. GQ-16 does not activate PPARα, PPARβ/δ, or RXRα.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Amato, A.A.,Rajagopalan, S.,Lin, J.Z., et al. GQ-16, a novel PPARγ ligand, promotes insulin sensitization without weight gain. The Journal of Biological Chemisty 1-20 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 418.3 |
| 分子式 | C19H16BrNO3S |
| CAS号 | 870554-67-9 |
| 稳定性 | ≥ 2 years |
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