| 货号 | 11832-1mg |
| 描述 | Corilagin is a polyphenol and hydrolyzable tannin that can be isolated from a variety of plants.1,2 It inhibits squalene epoxidase (IC50 = 4.0 µM), a key enzyme in cholesterol synthesis.1 Corilagin also has various anti-inflammatory and anti-cancer effects.2,3,4,5 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Abe, I.,Kashiwagi, Y.,Noguchi, H., et al. Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase. Journal of Natural Products 64(8), 1010-1014 (2001). 2.Gambari, R.,Borgatti, M.,Lampronti, I., et al. Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells. International Immunopharmacology 13(3), 308-315 (2012). 3.Xiao, H.T.,Lin, C.Y.,Ho, D.H.H., et al. Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitis. Journal of Natural Products 76(11), 2120-2125 (2013). 4.Jia, L.,Jin, H.,Zhou, J., et al. A potential anti-tumor herbal medicine, corilagin, inhibits ovarian cancer cell growth through blocking the TGF-β signaling pathways. BMC Complement.Altern.Med. 13, 33 (2013). 5.Gambari, R.,Hau, D.K.P.,Wong, W.Y., et al. Sensitization of Hep3B hepatoma cells to cisplatin and doxorubicin by corilagin. Phytotherapy Research 28(5), 781-783 (2014). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 634.5 |
| 分子式 | C27H22O18 |
| CAS号 | 23094-69-1 |
| 稳定性 | ≥ 2 years |
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