ML-7 (hydrochloride)
货号:
11801-1mg 基本售价:
350.0 元 规格:
1 mg
产品信息
概述货号 | 11801-1mg |
描述 | ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs.1,2 It exhibits a 10-fold more potent inhibition of MLCK than its parent compound ML-9 (Item No. 10010236).1,2 |
性能供应商 | Cayman |
应用文献 |
1.Saitoh, M.,Ishikawa, T.,Matsushima, S., et al. Selective inhibition of catalytic activity of smooth muscle myosin light chain kinase. The Journal of Biological Chemisty 262(16), 7796-7801 (1987). 2.Bain, J.,McLauchlan, H.,Elliot, M., et al. The specificities of protein kinase inhibitors: An update. Biochemistry Journal 371, 199-204 (2003).
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运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 452.7 |
分子式 | C15H17IN2O2S • HCl |
CAS号 | 110448-33-4 |
稳定性 | ≥ 2 years |
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