BRD4770
货号：
11787-1mg 基本售价：
350.0 元 规格：
1 mg
产品信息
概述| 货号 | 11787-1mg |
| 描述 | BRD4770 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, decreasing di- and trimethylation on lysine 9 of histone 3 (EC50 = 5 µM).1 Through its effects on EHMT2, BRD4770 induces senescence in the pancreatic cancer cell line PANC-1 without initiating apoptosis.1 It also blocks both anchorage-dependent and –independent proliferation of PANC-1 cells.1 |
| 别名 | HMTase Inhibitor VI; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yuan, Y.,Wang, Q.,Paulk, J., et al. A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma. ACS Chemical Biology 7(7), 1152-1157 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 413.5 |
| 分子式 | C25H23N3O3 |
| CAS号 | 1374601-40-7 |
| 稳定性 | ≥ 2 years |
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